I literally just finished Annie Jacobsen's book 'Biological War: A Scenario' last week where the central plot point is an accidental release of modified form of pneumonic plague from a lab in Siberia. Very coincidental timing, especially since it made me wonder how often labs like these have accidents and we never hear about them because it is cleaned up without issue.
> made me wonder how often labs like these have accidents and we never hear about them because it is cleaned up without issue.
Did anyone ever confirm if the lab in Wuhan China was the originator of COVID? I remember that was a rumor but never heard if there was anything to it.
I recently heard a scientist use a phrase something along the lines of “when two extraordinarily improbably events occur together, there is probably a connection”.
We’ll never know if the lab in Wuhan originated the virus. But it is awfully strange that the first patients of a novel pandemic coronavirus were workers at a lab conducting gain of function research on coronavirus.
Source on first patients being WIV workers? I think there was a US intelligence report that claimed several fell ill in Nov., some with incompatible symptoms, and with claims from WIV they didn't test positive for antibodies (not saying take those at face value). There's also the wet market and the sampling done in gutters around the different stalls and a whole competing story there, which is also the kind of scenario in the 2002 SARS outbreak.
>...were workers at a lab conducting gain of function research on coronavirus...
...with funding from a US group that discussed conducting this gain of function research in China using a spike protein at the furin cleavage site, a group whose members were appointed to come up with an explanation for what had happened.
It's difficult to say for sure, but the consensus is leaning towards zoonotic origin from a bat or pangolin in a wet market. (I'm not very well researched on this topic and don't have any formal background in it, so hedge accordingly)
Chinas actions following the event includes the destruction of evidence, refusal of access and using the WHO as their personal mouthpiece. Unless history is rewritten too, every textbook should clearly point to China.
I get downvoted every time I say this but the evidence doesn’t even prove it started in wuhan, or even China. It could of easily been brought here by the military games that happened before that
> A natural origin is still the more likely theory, said Professor David Robertson, head of viral genomics and bioinformatics at University of Glasgow.
So the suggestion is that it occurred naturally in China and then military games happened near Wuhan which spread the virus? Or did someone from Wuhan with ties/service in the Chinese military contract the virus locally and then spread it throughout China via travel to these military games?
Is that right, or is your point simply that it naturally occurred in China in the vicinity of Wuhan? I ask since the OP mentioned military games.
So breaks a test tube of live bacteria at an “anti-plague institute”, possible infects 100 colleagues, then when she developed plague like symptoms is taken to hospital and possibly infects 100 patients.
I think they need to investigate their safety protocols
> She reportedly told medical staff that she had accidentally broken a test tube containing live bacteria while collecting samples for testing.
> At least 197 people who may have had contact with her were reportedly placed under medical isolation, including more than 100 in hospital wards.
Was this a glass test tube? I understand why glass is probably the best material for the inner lining of containers that hold biological material, but I'm surprised that there aren't better solutions for hazardous material (e.g. an unbreakable, transparent polymer outer coating).
I believe the biggest reason to use glass is that it doesn't react with much stuff, but I've yet to see an explanation for why your idea wouldn't work. I imagine there could be problems with autoclaves (i.e. degradation of the polymer) and fear of chemical leaching.
Polymer coated glass is commonplace in chemistry labs for large containers of hazardous reagents held in storage. There's no chemical leaching concern because it's on the outside.
If anything, disposable plastic test tubes are the norm in microbiology labs at this point. No need to autoclave because they come sterile and you throw them away after a single use.
Plenty of plastic that's designed for it goes through the autoclave. For example micropipette tips. Nearly all of it is disposable single use so it only has to withstand a single cycle.
I don't think there is any actual evidence that it was a broken test tube because she would have started on prophylactic antibiotic treatment immediately.
Luckily you need to be in close contact with someone already very sick to catch it. It's not silent transmission like COVID. But maybe there is something different about this outbreak?
That's Russia we're talking about. You can have 1000 protocols and people will ignore them anyway. You can ask a ton of questions, like was she immunized before working with plague (Russia has pretty effective vaccines against all types) and if not why the heck not, why they use easily breakable test tubes to hold dangerous pathogens, how the incident with live biomaterial was not immediately reported and caused a lockdown, but they allowed waiting for symptoms and then going to a general hospital, etc., etc. - but the answer for all of that, I suspect, is: "it's Russia". For an American, it's hard to appreciate to what measure Russia is not a "safety culture" country.
How often does this sort of thing happen? I'm guessing more than we think, either because we forget the news stories we read or because it isn't reported.
Also ask how much is this failed route procedures because organisms or viri of this variety won't continue without human sustainment which is prone to human failures...
If you live in the Rocky Mountains try to avoid close contact with prairie dogs or animal carcasses and you'll be fine. If you catch it, get to a hospital quickly and take the antibiotics and you'll probably be fine. If you delay treatment you should use that time to get your affairs in order.
> The woman was identified as Daria Sh., a 27- or 28-year-old employee of the Irkutsk anti-plague institute, by the exiled news outlet Lyudi Baikala (People of Baikal) and pro-Kremlin broadcaster REN TV.
> She reportedly told medical staff that she had accidentally broken a test tube containing live bacteria while collecting samples for testing.
This is just weird. Plague is easily treated if antibiotics are given right away. I'm shocked that an anti-plague institute wouldn't have detailed and proactive plans in case of mishaps. Obviously I think it's likely that there is more to it than what's reported in the article, but I would find it truly baffling if within 60 seconds of her breaking that test tube that protocols weren't initiated to protect her, her colleagues and the community.
It's not clear if she even died from plague. The Russian-language version of the article lists various "versions" of what happened, and her breaking a test tube is only listed as one of the versions. Sounds like random rumors but at the same time, you can't trust the government either (which says no one has tested for plague positively). What's clear is that an employee at an "anti-plague' institute suddenly died from pneumonia-like symptoms, which certainly sounds suspicious but interpreting it as evidence of a plague infection may also be an overreaction
I'm assuming if its a bio-lab that its a gain of function version that may be immune to conventional antibiotics.
Actually went to a scout camp as a teenager (in the 80s) and one of our scouts got the plauge. Took a long while for the hospital to identify it and get him on heavy antibiotics because no one had seen it in real life before.
She probably didn't tell anybody she broke the tube, because, you know, they might yell at her and it may cost her a bit of money if they discover she was clumsy. So she just went home and when she felt bad, went to the hospital. Where nobody knew shit about the plague, as expected - when a person with respiratory symptoms in the autumn shows up in a hospital, nobody thinks "let's test her for plague". When she died, and when they learned where she worked, probably some major "oh shit!" lightbulbs gone up, but by then it was a done deed.
Did anyone ever confirm if the lab in Wuhan China was the originator of COVID? I remember that was a rumor but never heard if there was anything to it.
We’ll never know if the lab in Wuhan originated the virus. But it is awfully strange that the first patients of a novel pandemic coronavirus were workers at a lab conducting gain of function research on coronavirus.
...with funding from a US group that discussed conducting this gain of function research in China using a spike protein at the furin cleavage site, a group whose members were appointed to come up with an explanation for what had happened.
https://www.bbc.com/news/world-us-canada-64806903
> A natural origin is still the more likely theory, said Professor David Robertson, head of viral genomics and bioinformatics at University of Glasgow.
Is that right, or is your point simply that it naturally occurred in China in the vicinity of Wuhan? I ask since the OP mentioned military games.
I think they need to investigate their safety protocols
> She reportedly told medical staff that she had accidentally broken a test tube containing live bacteria while collecting samples for testing.
> At least 197 people who may have had contact with her were reportedly placed under medical isolation, including more than 100 in hospital wards.
If anything, disposable plastic test tubes are the norm in microbiology labs at this point. No need to autoclave because they come sterile and you throw them away after a single use.
Plenty of plastic that's designed for it goes through the autoclave. For example micropipette tips. Nearly all of it is disposable single use so it only has to withstand a single cycle.
Luckily you need to be in close contact with someone already very sick to catch it. It's not silent transmission like COVID. But maybe there is something different about this outbreak?
Is this a resistant strain?
https://emedicine.medscape.com/article/235627-medication#1
https://www.taiwannews.com.tw/news/4374289
Six errors contributed to this leak.
I thought at least fleas could transfer it between mammals?
[1]: https://whyy.org/segments/the-tragic-case-of-smallpoxs-final...
> She reportedly told medical staff that she had accidentally broken a test tube containing live bacteria while collecting samples for testing.
This is just weird. Plague is easily treated if antibiotics are given right away. I'm shocked that an anti-plague institute wouldn't have detailed and proactive plans in case of mishaps. Obviously I think it's likely that there is more to it than what's reported in the article, but I would find it truly baffling if within 60 seconds of her breaking that test tube that protocols weren't initiated to protect her, her colleagues and the community.
Of course, Russia...
Actually went to a scout camp as a teenager (in the 80s) and one of our scouts got the plauge. Took a long while for the hospital to identify it and get him on heavy antibiotics because no one had seen it in real life before.